Generation of a reporter cell line for detection of infectious varicella-zoster virus and its application to antiviral studies.
نویسندگان
چکیده
To simplify the titration of infectious varicella-zoster virus (VZV), we generated a reporter cell line that produced luciferase in a dose-dependent manner upon infection with cell-free VZV. A few VZV-infected cells were detectable by coculturing with the cell line. We demonstrated the usefulness of the cell line for antiviral studies.
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عنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 50 9 شماره
صفحات -
تاریخ انتشار 2006